Anti-pemphigus and Anti-atopic Potentials of Lycopi Herba Extract with MKK3 Inhibitory Activity in Human Keratinocyte HaCaT Cells

Eun Hye Kim, Seong Hwan Kim

Pemphigus is autoimmune blistering disease associated with autoantibodies (such as desmoglein 3 antibody) directed against the cell surface of keratinocytes, th...

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DOI: https://doi.org/10.20307/nps.2025.31.1.1

Cytotoxicity against MDA-MB-231 Breast Cancer Cells of Fungal Metabolites of Trichoderma sp. Collected from Medicinal Herbal Garden

Dahyeon Lee, Jin Woo Lee

sp. isolated from the herbal garden is one of the well-known soil fungi, and various metabolites produced by this genus, such as anthraquinones, azaphilones an...

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DOI: https://doi.org/10.20307/nps.2025.31.1.6

Prunus yedoensis Bark Water Extract Increases Hyaluronic Acid Synthesis and Skin Barrier-related Protein Levels

Ji Hyun Song, Yong Min Kim

Damage to barrier function due to a loss of moisture in the skin can lead to skin diseases, such as atopy and psoriasis. Hyaluronic acid (HA) has the ability to...

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DOI: https://doi.org/10.20307/nps.2025.31.1.13

15-Methylhexadecanoic Acid and Other Chemical Constituents from Calliandra calothyrsus (Meisn) (Fabaceae) with Their Antibacterial Activities

Armel Cyrille Tenkeu, Florence Déclaire Mabou, Andreea Veronica Dediu Botezatu, Jean-de-Dieu Tamokou, Germaine Matsuete Takongmo, Sophie Tomasi, Laurence Voutquenne-Nazabadioko, Rodica Mihaela Dinica, Apollinaire Tsopmo, David Ngnokam

A chemical study of the methanol extract from the leaves of led to the isolation of nine compounds including, 15-methylhexadecanoic acid (), isolated for the f...

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DOI: https://doi.org/10.20307/nps.2025.31.1.24

Cytotoxic Compounds Obtained through Cell Viability Screening of Fungal Extracts, Isolated from Urban Soil Samples I

Eun-Sook Kim, Jin Woo Lee

Soil microorganisms have been reported to interact with plants, playing key roles such as providing nutrients essential for plant growth and protecting them fro...

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DOI: https://doi.org/10.20307/nps.2025.31.1.32

Anti-inflammatory Constituents from Artemisia iwayomogi Kitamura: A Bioassay-guided Fractionation Study

Ngoc Khanh Vu, Thi Thanh Le, Trong Trieu Tran, Manh Tuan Ha, Jeong Ah Kim, Byung Sun Min

Bioassay-guided fractionation of the methanolic extract of Kitamura led to the isolation of 12 known compounds (‒). Notably, this study marks the first report ...

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DOI: https://doi.org/10.20307/nps.2025.31.1.43

Therapeutic Potential of Methanol Extract of Euonymus alatus in HT22 Cells Through Neuroprotective Mechanisms

Youn Sik Jung, Choong Je Ma

Oxidative stress, a key factor in the progression of brain diseases, induces apoptosis through multiple pathways. This study investigates the protective effects...

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DOI: https://doi.org/10.20307/nps.2025.31.1.49

Cognitive Enhancing Effects of Androst-16-ene-3,6-diol Isolated from Lysimachia christinae on Scopolamine-Induced Impaired Memory Function

Choong Je Ma

The ability of androst-16-ene-3,6-diol, a compound derived from , to enhance cognitive function was assessed in mice with scopolamine-induced amnesia. through b...

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DOI: https://doi.org/10.20307/nps.2025.31.1.55

PTP1B Inhibitory Activity of Flavonoids from the Roots of Astragalus membranaceus Bunge

Thi Ly Pham, Manh Tuan Ha, Byung Sun Min, Jeong Ah Kim

The roots of Bunge have long been used in herbal medicine for their diverse biological activities. Notably, its potential anti-diabetic properties have been ex...

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DOI: https://doi.org/10.20307/nps.2025.31.1.62