A β-(1→6)-Glucan-Rich Polysaccharide from Lentinula edodes (Shiitake Mushroom): Structural Diversity of Glucans

Sang Won Yeon, Hak Hyun Lee, Bang Yeon Hwang, Mi Kyeong Lee

A glucan-rich polysaccharide, designated LEP-1, was isolated from the fruiting bodies of by hot-water extraction followed by ion-exchange chromatography. Monos...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.177

α- and γ-Mangostins Suppress KRAS-Associated Signaling Pathways and Inhibit the Growth of Human Lung Cancer Cells

Ji Yun Lee, Ji-Young Hong, Young-Won Chin, Sang Kook Lee

Constitutive activation of multiple downstream survival pathways is a hallmark of KRAS-mutant non-small cell lung cancer (NSCLC), which often leads to poor resp...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.184

Lonicerin from Lonicera japonica Attenuates Scopolamine-Induced Memory Impairment in Mice

Choong Je Ma

This study examined whether lonicerin, a flavonoid glycoside isolated from , could reverse memory deficits induced by scopolamine administration in mice, drawin...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.191

Antiproliferative Effect of γ-Mangostin in Gastric Cancer Cells is Mediated by c-Met Signaling Pathway

Hee-Sung Chae, Si Young Park, Nam Sook Kang, Sun-Young Han, Young-Won Chin

Encoding the receptor for hepatocyte growth factor (HGF), the proto-oncogene c-Met represents one of the tyrosine kinases most commonly found to be dysregulated...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.198

Molecular Networking-Guided Isolation of Cyclic Hydroxamate Siderophores from the Marine-Derived Fungus Aspergillus terreus FM586

Chen Huo, Seo Yoon Lee, Hui Lei, Shugeng Cao, Ki Hyun Kim

Hydroxamate siderophores are low-molecular-weight iron-chelating metabolites that are widely produced by fungi to facilitate iron acquisition under iron-limited...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.206

Antofine and Related Phenanthroindolizidine Alkaloids in Cancer: Structure–Activity Relationships and Molecular Mechanisms

Jayoung Song

Antofine is a naturally occurring phenanthroindolizidine alkaloid with potent antiproliferative activity against a broad range of cancer cells. Despite its rema...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.211

Inhibitory Effects of Extracts of Ailanthus altissima var. altissima and Lycianthes beckneriana on Wnt/β-Catenin Signaling in Human Colorectal Cancer Cells

Seungcheol Jeong, Joonhwan Yoon, Haedam Choi, Hyunjoo Lee, Jongbin Park, Sang Kook Lee, Won Kyung Kim

The canonical Wnt/β-catenin signaling pathway is aberrantly activated in most colorectal cancers and is therefore regarded as an attractive molecular target for...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.220

Isolation of Chemical Constituents from Athyrium yokoscense and Their Inhibitory Effects on Nitrite Accumulation in LPS-Stimulated BV2 Microglial Cells

Hyunwoo Kim, Woong Sub Byun

Three phloroglucinol derivatives, aspidinol B (), aspidinol P (), and methylene-bis-aspidinol B (), together with one flavonoid, angophorol (), were isolated fr...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.228

Sclerotiorin-Type Azaphilones from Penicillium sp. with Their Anticancer Activities

Se-Jeong Hwang, Pritam Sarkar, Kun Taek Park, Joonseong Hur, Jin Woo Lee, Na-Lee Ka, Yun-Seo Kil

As part of ongoing efforts to discover fungal-derived antibacterial and anticancer natural products, a soil-derived fungal strain ( sp.) was identified as a hit...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.236

Anti-inflammatory Effects of Fermented Products with Brassica rapa subsp. pekinensis Regulating Inflammation

Thinhulinh Dang, Ducdat Le, Mina Lee

This research assessed the anti-inflammatory effectiveness of fermented products of subsp. utilizing a murine model of dextran sulfate sodium (DSS)-induced co...

PDFHTMLPubReaderePub

DOI: https://doi.org/10.20307/nps.2026.32.3.243